Preparation of α,β,γ,γ-tetrasubstituted α,β-unsaturated γ-lactams via a tandem or one-pot oxidative Ritter reaction/Knoevenagel condensation.

IF 2.7 3区化学 Q1 CHEMISTRY, ORGANIC

Organic & Biomolecular Chemistry Pub Date : 2025-10-08 DOI:10.1039/d5ob01300c

Yu-Ting Chen, Yue-Hong Hu, Zhang-Yan Gan, Chun-Yu Yu, Juxin Mo, Meng-En Chen, Xiao-Ming Zhang, Fu-Min Zhang

引用次数: 0

Abstract

An efficient synthesis of α,β,γ,γ-tetrasubstituted α,β-unsaturated γ-lactams has been developed through a tandem or one-pot oxidative Ritter reaction/Knoevenagel condensation of functionalized nitriles and 2-arylketones for the first time.

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串联或单锅氧化Ritter反应/Knoevenagel缩合制备α，β,γ，γ-四取代α，β-不饱和γ-内酰胺。

本文首次采用串联或一锅氧化Ritter反应/Knoevenagel缩合法合成了功能化腈和2-芳基酮的四取代α，β,γ，γ-不饱和γ-内酰胺。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Organic & Biomolecular Chemistry 化学-有机化学

CiteScore

5.50

自引率

9.40%

发文量

1056

审稿时长

1.3 months

期刊介绍： Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.