Gonzalo de Luna, Isabelle Genty, Vincent Parinet, Florence Beckerich, Rabah Redjoul, Anoosha Habibi, Sihem Iles, Geneviève Derumeaux, Nicolas Lellouche, Thibaut Moulin, Laurent Boyer, Sébastien Maury, Pablo Bartolucci, Thomas d'Humières
{"title":"Haplo-Identical Stem Cell Transplant Resolves Ventricular Arrhythmias and Dysfunction in a Sickle Cell Anemia Patient: Case Report and Discussion","authors":"Gonzalo de Luna, Isabelle Genty, Vincent Parinet, Florence Beckerich, Rabah Redjoul, Anoosha Habibi, Sihem Iles, Geneviève Derumeaux, Nicolas Lellouche, Thibaut Moulin, Laurent Boyer, Sébastien Maury, Pablo Bartolucci, Thomas d'Humières","doi":"10.1002/jha2.70161","DOIUrl":null,"url":null,"abstract":"<p>A Sickle Cell Anemia patient with severe ventricular arrhythmia and left ventricular dysfunction achieved rapid, complete cardiac recovery after haplo-identical stem cell transplantation, raising questions about SCA cardiac pathophysiology and highlighting the potential for reversible cardiac complications following curative treatment.</p><p><b>Trial Registration</b>: The authors have confirmed clinical trial registration is not needed for this submission</p>","PeriodicalId":72883,"journal":{"name":"EJHaem","volume":"6 5","pages":""},"PeriodicalIF":1.2000,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498570/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"EJHaem","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jha2.70161","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A Sickle Cell Anemia patient with severe ventricular arrhythmia and left ventricular dysfunction achieved rapid, complete cardiac recovery after haplo-identical stem cell transplantation, raising questions about SCA cardiac pathophysiology and highlighting the potential for reversible cardiac complications following curative treatment.
Trial Registration: The authors have confirmed clinical trial registration is not needed for this submission