From genetic predisposition to mental health: Human cortical development in vitro.

IF 15 1区医学 Q1 NEUROSCIENCES

Neuron Pub Date : 2025-10-01 DOI:10.1016/j.neuron.2025.08.025

Arghya Mukherjee, Pico Caroni

引用次数: 0

Abstract

In this issue of Neuron, Walsh et al.¹ show how an improved human forebrain assembloid system that includes bona fide developing and differentiated cortical parvalbumin interneurons can be harnessed to investigate early human cortical development in genetic models of schizophrenia.

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从遗传易感性到心理健康：体外人类皮质发育

在本期《神经元》杂志上，Walsh等人展示了如何利用一个改进的人类前脑集合体系统，包括真正发育和分化的皮层小白蛋白中间神经元，来研究精神分裂症遗传模型中的早期人类皮层发育。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neuron 医学-神经科学

CiteScore

24.50

自引率

3.10%

发文量

382

审稿时长

1 months

期刊介绍： Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.