Glycogenic Hepatopathy: A Case Report of a Rare Complication in Uncontrolled Diabetes

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL

Clinical Case Reports Pub Date : 2025-10-01 DOI:10.1002/ccr3.71079

Mais Musleh, Amani AlMokbel

引用次数: 0

Abstract

Glycogenic hepatopathy (GH) is an underrecognized yet reversible cause of hepatomegaly and transaminase elevation in adolescents with poorly controlled type 1 diabetes mellitus (T1DM). While liver biopsy is often utilized to exclude other hepatic pathologies, it can also aid in confirming GH when noninvasive findings are inconclusive. We present a case of an 18-year-old male with type 1 diabetes, whose poorly controlled condition led to the development of GH. The diagnosis was confirmed through a liver biopsy, emphasizing the significance of early detection and proper glycemic management in preventing irreversible liver damage.

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糖原性肝病：1例未控制糖尿病罕见并发症报告。

糖原性肝病（GH）是控制不良的青少年1型糖尿病（T1DM）患者肝肿大和转氨酶升高的一种未被充分认识但可逆的病因。虽然肝活检常用于排除其他肝脏病变，但当非侵入性检查结果不确定时，它也可以帮助确认生长激素。我们报告一例18岁男性1型糖尿病患者，其控制不良导致生长激素的发展。通过肝活检确认诊断，强调早期发现和适当的血糖管理对预防不可逆肝损害的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Case Reports MEDICINE, GENERAL & INTERNAL-

自引率

14.30%

发文量

1268

审稿时长

13 weeks

期刊介绍： Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).