Beyond the Bone Marrow: Uncommon Manifestation of Multiple Myeloma-A Case Report of Extramedullary Esophageal Involvement.

IF 0.5 Q4 GASTROENTEROLOGY & HEPATOLOGY

ACG Case Reports Journal Pub Date : 2025-10-01 DOI:10.14309/crj.0000000000001837

Kelly Fan, Maya Mahmoud, Mahmoud Y Madi, Antonio Cheesman Rocca, Wissam Kiwan

引用次数: 0

Abstract

Extramedullary multiple myeloma is an aggressive form of myeloma, with gastrointestinal involvement occurring in less than 5% of cases. We present a 60-year-old man admitted after a syncopal episode. Imaging revealed a large esophageal mass and multiple lytic bone lesions. Biopsy confirmed IgG kappa multiple myeloma without bone marrow involvement. Despite chemotherapy, the disease progressed, and the patient passed away 6 months later. Extramedullary esophageal involvement in the setting of advanced multiple myeloma is rare, with only 2 prior reported cases.

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骨髓外：多发性骨髓瘤的罕见表现：髓外食管受累1例。

髓外多发性骨髓瘤是一种侵袭性骨髓瘤，在不到5%的病例中累及胃肠道。我们报告一位60岁的男性在晕厥发作后入院。影像显示一大块食道肿块及多处溶解性骨病变。活检证实IgG kappa多发性骨髓瘤，未累及骨髓。尽管进行了化疗，但病情仍在恶化，患者于6个月后去世。晚期多发性骨髓瘤的髓外食管受累是罕见的，只有2例报告。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-

自引率

14.30%

发文量

170

审稿时长

12 weeks

期刊介绍： ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.