K₂S₂O₈/DMSO-Mediated Organic Transformations: A Comprehensive Report.

IF 3.3 3区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemistry - An Asian Journal Pub Date : 2025-09-30 DOI:10.1002/asia.70351

Pragati Kushwaha, Rashi

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引用次数: 0

Abstract

The pursuit of sustainable and efficient methodologies for C─C and C─X bond formations, as well as other complex functionalizations, remains a fundamental goal in modern organic chemistry. In recent years, potassium persulfate (K₂S₂O₈) and dimethyl sulfoxide (DMSO) catalytic system has attracted considerable attention owing to its environmentally benign nature, high efficiency, affordability, and mild reaction conditions. This catalytic combination has been effectively employed in a wide range of transformations, including cyclization, C─C/C─X coupling, oxygenation, and deoxygenation reactions, etc. These successes have firmly established K₂S₂O₈/DMSO as a green, efficient, and versatile system for organic transformations. This review provides a comprehensive overview of recent developments utilizing this catalytic system, mechanistic insights, synthetic applications, and outlining future directions. With this, it aims to serve as a key resource for further development to more sustainable approaches in modern organic synthetic chemistry.

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K2S2O8/ dmso介导的有机转化：综合报告。

追求C─C和C─X键形成的可持续和有效的方法，以及其他复杂的官能化，仍然是现代有机化学的基本目标。近年来，过硫酸钾(K2S2O8) -二甲基亚砜（DMSO）催化体系因其环保、高效、价格合理、反应条件温和等特点而备受关注。这种催化组合已有效地应用于广泛的转化，包括环化、C─C/C─X偶联、氧化和脱氧反应等。这些成功已经牢固地确立了K2S2O8/DMSO作为一种绿色，高效和通用的有机转化系统。本文综述了该催化体系的最新发展、机理、合成应用，并概述了未来的发展方向。有了这个，它的目的是作为一个关键资源，进一步发展更可持续的方法，在现代有机合成化学。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chemistry - An Asian Journal 化学-化学综合

CiteScore

7.00

自引率

2.40%

发文量

535

审稿时长

1.3 months

期刊介绍： Chemistry—An Asian Journal is an international high-impact journal for chemistry in its broadest sense. The journal covers all aspects of chemistry from biochemistry through organic and inorganic chemistry to physical chemistry, including interdisciplinary topics. Chemistry—An Asian Journal publishes Full Papers, Communications, and Focus Reviews. A professional editorial team headed by Dr. Theresa Kueckmann and an Editorial Board (headed by Professor Susumu Kitagawa) ensure the highest quality of the peer-review process, the contents and the production of the journal. Chemistry—An Asian Journal is published on behalf of the Asian Chemical Editorial Society (ACES), an association of numerous Asian chemical societies, and supported by the Gesellschaft Deutscher Chemiker (GDCh, German Chemical Society), ChemPubSoc Europe, and the Federation of Asian Chemical Societies (FACS).