{"title":"High prevalence of renal amyloidosis in cats in an overcrowded colony.","authors":"Ayami Yutsudo, Natsume Kurahara, Shigeki Yamano, Osamu Yamato, Noriaki Miyoshi, Tatsuro Hifumi, Akira Yabuki","doi":"10.1292/jvms.25-0044","DOIUrl":null,"url":null,"abstract":"<p><p>Multiple cats in an overcrowded colony died of acute kidney injury with renal amyloidosis. To investigate the etiology of these deaths, we performed histological analysis of the kidneys of 27 colony cats and 29 noncolony cats (8 with acute kidney injury, 9 with chronic kidney disease, and 12 nonazotemic). Congo red-positive amyloid deposition was observed prominently in the glomeruli and cortical and medullary interstitium and was identified as AA amyloid using permanence. The prevalence and severity of renal amyloidosis were significantly higher in colony cats than in noncolony cats. Feline immunodeficiency virus showed no association with feline leukemia virus infection. Based on our results, adverse environmental conditions may accelerate the incidence of feline renal amyloidosis.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1000,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Veterinary Medical Science","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1292/jvms.25-0044","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Multiple cats in an overcrowded colony died of acute kidney injury with renal amyloidosis. To investigate the etiology of these deaths, we performed histological analysis of the kidneys of 27 colony cats and 29 noncolony cats (8 with acute kidney injury, 9 with chronic kidney disease, and 12 nonazotemic). Congo red-positive amyloid deposition was observed prominently in the glomeruli and cortical and medullary interstitium and was identified as AA amyloid using permanence. The prevalence and severity of renal amyloidosis were significantly higher in colony cats than in noncolony cats. Feline immunodeficiency virus showed no association with feline leukemia virus infection. Based on our results, adverse environmental conditions may accelerate the incidence of feline renal amyloidosis.
期刊介绍：
JVMS is a peer-reviewed journal and publishes a variety of papers on veterinary science from basic research to applied science and clinical research. JVMS is published monthly and consists of twelve issues per year. Papers are from the areas of anatomy, physiology, pharmacology, toxicology, pathology, immunology, microbiology, virology, parasitology, internal medicine, surgery, clinical pathology, theriogenology, avian disease, public health, ethology, and laboratory animal science. Although JVMS has played a role in publishing the scientific achievements of Japanese researchers and clinicians for many years, it now also accepts papers submitted from all over the world.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
