Fine-scale regional frequency of the MUC5B promoter variant correlates with healthcare burden of idiopathic pulmonary fibrosis.

IF 4 3区医学 Q1 RESPIRATORY SYSTEM

ERJ Open Research Pub Date : 2025-09-22 eCollection Date: 2025-09-01 DOI:10.1183/23120541.00305-2025

Edmund Gilbert, Aoife Carolan, Mari Ozaki, Niamh Logan, Khaled Musameh, Helen O'Brien, Wan Lin Ng, Jisha Jasmin, Cormac McCarthy, Michael P Keane, David A Schwartz, Michael T Henry, Killian Hurley

引用次数: 0

Abstract

Mapping the fine-scale geographic distribution of the MUC5B promoter variant across the island of Ireland demonstrated a strong correlation with IPF hospital discharge. This type of risk variant mapping could support more precise healthcare planning. https://bit.ly/43tZYI7.

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MUC5B启动子变异的精细区域频率与特发性肺纤维化的医疗负担相关

绘制整个爱尔兰岛MUC5B启动子变异的精细地理分布图显示与IPF出院有很强的相关性。这种类型的风险变量映射可以支持更精确的医疗保健规划。https://bit.ly/43tZYI7。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ERJ Open Research Medicine-Pulmonary and Respiratory Medicine

CiteScore

6.20

自引率

4.30%

发文量

273

审稿时长

8 weeks

期刊介绍： ERJ Open Research is a fully open access original research journal, published online by the European Respiratory Society. The journal aims to publish high-quality work in all fields of respiratory science and medicine, covering basic science, clinical translational science and clinical medicine. The journal was created to help fulfil the ERS objective to disseminate scientific and educational material to its members and to the medical community, but also to provide researchers with an affordable open access specialty journal in which to publish their work.