{"title":"Embryonic development: Tracing the origin of epiblast cells.","authors":"Violaine Paulus, Claire Chazaud","doi":"10.1016/j.cub.2025.08.018","DOIUrl":null,"url":null,"abstract":"<p><p>The epiblast is the source of all the cells of our bodies and of the pluripotent embryonic stem cells. Novel work using fluorescent reporter-based cell tracking supports a stochastic mechanism for epiblast differentiation and reveals SOX2 as the most obvious marker.</p>","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":"35 18","pages":"R892-R895"},"PeriodicalIF":7.5000,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Biology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1016/j.cub.2025.08.018","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The epiblast is the source of all the cells of our bodies and of the pluripotent embryonic stem cells. Novel work using fluorescent reporter-based cell tracking supports a stochastic mechanism for epiblast differentiation and reveals SOX2 as the most obvious marker.
期刊介绍:
Current Biology is a comprehensive journal that showcases original research in various disciplines of biology. It provides a platform for scientists to disseminate their groundbreaking findings and promotes interdisciplinary communication. The journal publishes articles of general interest, encompassing diverse fields of biology. Moreover, it offers accessible editorial pieces that are specifically designed to enlighten non-specialist readers.