Front Cover: Novel Ambergris Odorants Devoid of Ketal Functions: Sustainable Synthesis of 4-(α-Cedren-8-yl)Butan-2-Ones and Potent Methoxy Derivatives by Claisen Chemistry (Eur. J. Org. Chem. 33/2025)
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Abstract
The Front Cover features a highly potent methoxy-substituted constituent of the novel ambergris odorant “Ambronova”, docked to the olfactory receptor OR7A17, assumed to be responsible for eliciting ambergris odor sensations. To remain in the cosmic context, the receptor surface was rendered as an emission nebula of a supernova remnant, and its excellent fit with the molecular features demonstrates the high degree of complementarity with the bifunctional methoxy ketone that mimics a ketal function. More information can be found in the Research Article by P. Kraft and co-workers (DOI: 10.1002/ejoc.202500548).
期刊介绍：
The European Journal of Organic Chemistry (2019 ISI Impact Factor 2.889) publishes Full Papers, Communications, and Minireviews from the entire spectrum of synthetic organic, bioorganic and physical-organic chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies.
The following journals have been merged to form two leading journals, the European Journal of Organic Chemistry and the European Journal of Inorganic Chemistry:
Liebigs Annalen
Bulletin des Sociétés Chimiques Belges
Bulletin de la Société Chimique de France
Gazzetta Chimica Italiana
Recueil des Travaux Chimiques des Pays-Bas
Anales de Química
Chimika Chronika
Revista Portuguesa de Química
ACH—Models in Chemistry
Polish Journal of Chemistry.
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