Multifocal cutaneous leishmaniasis in a patient treated with golimumab for psoriaticarthritis.

IF 0.6 4区医学 Q4 PATHOLOGY

Polish Journal of Pathology Pub Date : 2025-01-01 DOI:10.5114/pjp.2025.153977

Veronica Forte, Anna Silvia Biamonte, Massimo Menichini, Fabrizio Liberati, Luca Ventura

引用次数: 0

Abstract

Leishmaniasis is a zoonosis caused by protozoans transmitted by sandflies. Immu-nosuppression is a risk factor for developing leishmaniasis in patients treated with TNF inhibitors for autoimmune diseases. A 65-year-old man with a 14-year histo-ry of psoriatic arthritis in treatment with methotrexate, treated with golimumab during the last 2.5 years, presented ulcerations of the buttocks and upper back. Histopathological findings allowed us to yield the diagnosis of cutaneous leishman-iasis. Therapy was suspended and the patient underwent appropriate treatment. Five cases of leishmaniasis in patients treated with golimumab were reported in literature and ten cases were mentioned in retrospective reviews.

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多局灶性皮肤利什曼病的患者治疗银屑病关节炎戈利姆单抗。

利什曼病是一种由白蛉传播的原生动物引起的人畜共患病。免疫无抑制是使用TNF抑制剂治疗自身免疫性疾病的患者发生利什曼病的危险因素。65岁男性，有14年银屑病关节炎病史，接受甲氨蝶呤治疗，过去2.5年接受戈利姆单抗治疗，出现臀部和上背部溃疡。组织病理学结果允许我们得出皮肤利什曼病的诊断。暂停治疗，患者接受适当治疗。文献报道了5例接受戈利姆单抗治疗的患者发生利什曼病，回顾性评价中提到了10例。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Polish Journal of Pathology PATHOLOGY-

CiteScore

1.00

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Polish Journal of Pathology is an official magazine of the Polish Association of Pathologists and the Polish Branch of the International Academy of Pathology. For the last 18 years of its presence on the market it has published more than 360 original papers and scientific reports, often quoted in reviewed foreign magazines. A new extended Scientific Board of the quarterly magazine comprises people with recognised achievements in pathomorphology and biology, including molecular biology and cytogenetics, as well as clinical oncology. Polish scientists who are working abroad and are international authorities have also been invited. Apart from presenting scientific reports, the magazine will also play a didactic and training role.