Theranostic Application of Radiohalogens in Nuclear Medicine.

IF 2.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Nuclear Medicine and Molecular Imaging Pub Date : 2025-10-01 Epub Date: 2025-08-16 DOI:10.1007/s13139-025-00937-x

Choong Mo Kang

引用次数: 0

Abstract

Radiohalogens, including fluorine-18 (F-18) and radioiodine (I-123, I-124, and I-131), have been utilized widely for both diagnostic imaging and targeted radionuclide therapy owing to their favorable nuclear properties, well-established radiochemistry, and broad applicability to biomolecules. Among the diverse radionuclides utilized in this field, the production of astatine-211, a promising alpha-emitting radiohalogen, has expanded globally, stimulating a growing interest in theranostic applications that leverage the unique properties of radiohalogens. This review article provides an overview of radiohalogens in nuclear medicine, discussing their current status and future prospects in theranostic radiopharmaceuticals.

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放射性卤素在核医学中的治疗应用。

放射性卤素，包括氟-18 （F-18）和放射性碘（I-123、I-124和I-131），由于其良好的核特性、完善的放射化学和对生物分子的广泛适用性，已广泛用于诊断成像和靶向放射性核素治疗。在这一领域使用的各种放射性核素中，有前途的α发射放射性卤素砹-211的生产已在全球范围内扩大，激发了人们对利用放射性卤素独特性质的治疗应用的日益浓厚的兴趣。本文综述了放射性卤素在核医学中的应用现状，并对其在放射性药物治疗中的应用前景进行了展望。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nuclear Medicine and Molecular Imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

2.20

自引率

7.70%

发文量

期刊介绍： Nuclear Medicine and Molecular Imaging (Nucl Med Mol Imaging) is an official journal of the Korean Society of Nuclear Medicine, which bimonthly publishes papers on February, April, June, August, October, and December about nuclear medicine and related sciences such as radiochemistry, radiopharmacy, dosimetry and pharmacokinetics / pharmacodynamics of radiopharmaceuticals, nuclear and molecular imaging analysis, nuclear and molecular imaging instrumentation, radiation biology and radionuclide therapy. The journal specially welcomes works of artificial intelligence applied to nuclear medicine. The journal will also welcome original works relating to molecular imaging research such as the development of molecular imaging probes, reporter imaging assays, imaging cell trafficking, imaging endo(exo)genous gene expression, and imaging signal transduction. Nucl Med Mol Imaging publishes the following types of papers: original articles, reviews, case reports, editorials, interesting images, and letters to the editor. The Korean Society of Nuclear Medicine (KSNM) KSNM is a scientific and professional organization founded in 1961 and a member of the Korean Academy of Medical Sciences of the Korean Medical Association which was established by The Medical Services Law. The aims of KSNM are the promotion of nuclear medicine and cooperation of each member. The business of KSNM includes holding academic meetings and symposia, the publication of journals and books, planning and research of promoting science and health, and training and qualification of nuclear medicine specialists.