Identification and treatment of polycystic ovary syndrome in adolescents: A primer for the lipidologist

IF 4.6 3区医学 Q2 PHARMACOLOGY & PHARMACY

Journal of clinical lipidology Pub Date : 2025-09-01 DOI:10.1016/j.jacl.2025.04.184

Sarah E. Swauger MD, Nancy A. Crimmins MD

引用次数: 0

Abstract

BACKGROUND

Polycystic ovary syndrome (PCOS) is a disorder characterized by menstrual irregularity andhyperandrogenism.

MATERIAL

In this article, we aim to review the clinical features of PCOS and the co-morbidities that often accompany the condition.

FINDINGS

Insulin resistance and obesity have an influence on disease pathogenesis, and many adolescents with PCOS have metabolic comorbidities (type 2 diabetes, liver disease, cardiovascular disease).

CONCLUSION

Early identification and treatment of adolescent females with PCOS can improve metabolic health, mental health, and fertility outcomes, with an emphasis on the importance of lifestyle modifications, pharmacologic use when indicated, and multidisciplinary care.

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青少年多囊卵巢综合征的鉴别和治疗：脂质学家的入门读物

背景：多囊卵巢综合征（PCOS）是一种以月经不规律和雄激素过多为特征的疾病。在这篇文章中，我们的目的是回顾多囊卵巢综合征的临床特点和合并症，往往伴随的条件。发现胰岛素抵抗和肥胖对多囊卵巢综合征的发病机制有影响，许多青少年多囊卵巢综合征伴有代谢性合并症（2型糖尿病、肝病、心血管疾病）。结论早期发现和治疗青春期女性多囊卵巢综合征可改善代谢健康、心理健康和生育结局，并强调改变生活方式、适时使用药物和多学科护理的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of clinical lipidology 医学-药学

CiteScore

7.00

自引率

6.80%

发文量

209

审稿时长

49 days

期刊介绍： Because the scope of clinical lipidology is broad, the topics addressed by the Journal are equally diverse. Typical articles explore lipidology as it is practiced in the treatment setting, recent developments in pharmacological research, reports of treatment and trials, case studies, the impact of lifestyle modification, and similar academic material of interest to the practitioner. Sections of Journal of clinical lipidology will address pioneering studies and the clinicians who conduct them, case studies, ethical standards and conduct, professional guidance such as ATP and NCEP, editorial commentary, letters from readers, National Lipid Association (NLA) news and upcoming event information, as well as abstracts from the NLA annual scientific sessions and the scientific forums held by its chapters, when appropriate.