A Syngeneic Mouse Model of CAR-T Cell Therapy Containing a Translatable Dual Human/Mouse Reactive sdAb Binder in Vk*MYC Mice Reveals Clinically-Relevant Microenvironment Changes

IF 2.7 4区 医学 Q2 HEMATOLOGY
Lorenzo Lindo, Daniel Waller, Erin Meermeier, Lauren Wilkinson, Silvia Selleri, Jennifer Rahn, Mehdi Arbabi-Ghahroudi, Scott McComb, Leif Bergsagel, Marta Chesi, Nicolas Jacquelot, Laura Evgin, Kevin Hay
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引用次数: 0
含有可翻译的双人/小鼠反应性sdAb结合物的Vk*MYC小鼠CAR-T细胞治疗的同基因小鼠模型揭示了临床相关的微环境变化
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.70
自引率
3.70%
发文量
1606
审稿时长
26 days
期刊介绍: Clinical Lymphoma, Myeloma & Leukemia is a peer-reviewed monthly journal that publishes original articles describing various aspects of clinical and translational research of lymphoma, myeloma and leukemia. Clinical Lymphoma, Myeloma & Leukemia is devoted to articles on detection, diagnosis, prevention, and treatment of lymphoma, myeloma, leukemia and related disorders including macroglobulinemia, amyloidosis, and plasma-cell dyscrasias. The main emphasis is on recent scientific developments in all areas related to lymphoma, myeloma and leukemia. Specific areas of interest include clinical research and mechanistic approaches; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; and integration of various approaches.
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