Lower non-invasive estimated P_mus predicts extubation failure in mechanically ventilated ICU patients.

IF 1.4 Q3 CRITICAL CARE MEDICINE

Journal of the Intensive Care Society Pub Date : 2025-09-16 DOI:10.1177/17511437251377989

Graziela Müller, Manoela Bonato Zocoli, Jéssica Magnante, Geovana Teo Zamprogna, Silvano Altair do Nascimento, Gustavo Bruno Rático, Ewan C Goligher, Antuani Rafael Baptistella

引用次数: 0

Abstract

We evaluated whether non-invasive estimated inspiratory muscle pressure (P_mus) predicts extubation outcomes in ICU patients. Estimated P_mus, reflecting the pressure generated by respiratory muscles, was measured before and after the spontaneous breathing trial (SBT). Lower pre-SBT estimated P_mus (<4.1 cmH₂O) and post-SBT (<4.4 cmH₂O) were associated with extubation failure (AUC ≈ 0.73). P0.1 and dynamic transpulmonary pressure (P_L,dyn) showed no significant association. Estimated P_mus offers a simple bedside method to assess inspiratory muscle strength and may help identify patients at risk of extubation failure. Further multicenter studies are needed to validate these findings.

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低无创Pmus可预测机械通气ICU患者拔管失败。

我们评估了非侵入性估计吸气肌压力（Pmus）是否能预测ICU患者拔管结果。在自发呼吸试验（SBT）前后测量反映呼吸肌产生压力的估计Pmus。较低的sbt前估计Pmus （L,dyn）没有显着关联。估计Pmus提供了一种简单的床边方法来评估吸气肌力量，并可能有助于识别有拔管失败风险的患者。需要进一步的多中心研究来验证这些发现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the Intensive Care Society Nursing-Critical Care Nursing

CiteScore

4.40

自引率

0.00%

发文量

期刊介绍： The Journal of the Intensive Care Society (JICS) is an international, peer-reviewed journal that strives to disseminate clinically and scientifically relevant peer-reviewed research, evaluation, experience and opinion to all staff working in the field of intensive care medicine. Our aim is to inform clinicians on the provision of best practice and provide direction for innovative scientific research in what is one of the broadest and most multi-disciplinary healthcare specialties. While original articles and systematic reviews lie at the heart of the Journal, we also value and recognise the need for opinion articles, case reports and correspondence to guide clinically and scientifically important areas in which conclusive evidence is lacking. The style of the Journal is based on its founding mission statement to ‘instruct, inform and entertain by encompassing the best aspects of both tabloid and broadsheet''.

Lower non-invasive estimated Pmus predicts extubation failure in mechanically ventilated ICU patients.

Abstract

Lower non-invasive estimated P_mus predicts extubation failure in mechanically ventilated ICU patients.