Recent insights in the development and functions of insect hemocytes

IF 4.8 1区农林科学 Q1 BIOLOGY

Current opinion in insect science Pub Date : 2025-09-15 DOI:10.1016/j.cois.2025.101434

Michael R Strand

引用次数: 0

Abstract

Hemocytes mediate defense responses that are collectively referred to as cellular immunity. Here, I highlight recent progress in the study of hemocyte ontogeny and function. Studies conducted primarily in D. melanogaster, mosquitoes, and Lepidoptera identify a number of transcription factors and signaling pathways that regulate hemocyte differentiation and proliferation. Single-cell RNA sequencing studies identify genes that distinguish transitional states in different hemocyte populations and changes that occur during immune responses. Several new studies expand the understanding of the functions of sessile hemocytes. Recent results also enhance understanding of the signaling pathways that regulate hemocyte functions.

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昆虫血细胞发育和功能的最新研究进展。

血细胞介导的防御反应统称为细胞免疫。在此，我将重点介绍血细胞发生和功能的最新研究进展。主要在黑腹大蠊、蚊子和鳞翅目中进行的研究发现了许多调节血细胞分化和增殖的转录因子和信号通路。最近的单细胞RNA测序研究确定了区分不同血细胞群体的过渡状态和免疫反应期间发生的变化的基因。一些新的研究扩大了对无梗血细胞功能的理解。最近的研究结果也增强了对调节血细胞功能的信号通路的理解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current opinion in insect science BIOLOGYECOLOGYENTOMOLOGY-ECOLOGY

CiteScore

10.40

自引率

1.90%

发文量

113

期刊介绍： Current Opinion in Insect Science is a new systematic review journal that aims to provide specialists with a unique and educational platform to keep up–to–date with the expanding volume of information published in the field of Insect Science. As this is such a broad discipline, we have determined themed sections each of which is reviewed once a year. The following 11 areas are covered by Current Opinion in Insect Science. -Ecology -Insect genomics -Global Change Biology -Molecular Physiology (Including Immunity) -Pests and Resistance -Parasites, Parasitoids and Biological Control -Behavioural Ecology -Development and Regulation -Social Insects -Neuroscience -Vectors and Medical and Veterinary Entomology There is also a section that changes every year to reflect hot topics in the field. Section Editors, who are major authorities in their area, are appointed by the Editors of the journal. They divide their section into a number of topics, ensuring that the field is comprehensively covered and that all issues of current importance are emphasized. Section Editors commission articles from leading scientists on each topic that they have selected and the commissioned authors write short review articles in which they present recent developments in their subject, emphasizing the aspects that, in their opinion, are most important. In addition, they provide short annotations to the papers that they consider to be most interesting from all those published in their topic over the previous year.