A metabolic syndrome: Understanding host factors that drive mortality in tuberculosis meningitis.

IF 11.8 Q1 MEDICINE, RESEARCH & EXPERIMENTAL

Med Pub Date : 2025-09-12 DOI:10.1016/j.medj.2025.100705

Jeffrey M Collins, Russell R Kempker

引用次数: 0

Abstract

Cerebrospinal fluid metabolomics uncovered distinct short chain fatty acids and amino acids strongly associated with mortality in persons with tuberculosis meningitis (TBM). These findings from Nhat et al. highlight the critical role of energy metabolism in the host response to TBM and provide new avenues to explore and target for host-directed therapy.

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代谢综合征：了解驱动结核性脑膜炎死亡率的宿主因素。

脑脊液代谢组学揭示了不同的短链脂肪酸和氨基酸与结核性脑膜炎（TBM）患者的死亡率密切相关。Nhat等人的这些发现强调了能量代谢在宿主对TBM反应中的关键作用，并为探索和靶向宿主定向治疗提供了新的途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Med MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

17.70

自引率

0.60%

发文量

102

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