Non-muscle myosin II is a promising therapeutic target.

IF 19.9 1区医学 Q1 PHARMACOLOGY & PHARMACY

Trends in pharmacological sciences Pub Date : 2025-10-01 Epub Date: 2025-09-12 DOI:10.1016/j.tips.2025.08.011

Courtney A Miller, Alfredo Quinones-Hinojosa, Steven S Rosenfeld

引用次数: 0

Abstract

Non-muscle myosin II (NMII) comprises a family of cytoplasmic motors with important roles in both normal biology and disease. In this forum article we describe recent developments that validate NMII as a therapeutic target, and we illustrate how this validation can identify novel and translationally viable approaches to treat a variety of diseases.

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非肌球蛋白II是一个很有前景的治疗靶点。

非肌球蛋白II （NMII）由细胞质马达家族组成，在正常生物学和疾病中都起着重要作用。在这篇论坛文章中，我们描述了验证NMII作为治疗靶点的最新进展，并说明了这种验证如何识别新的和翻译上可行的方法来治疗各种疾病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in pharmacological sciences 医学-药学

CiteScore

23.90

自引率

0.70%

发文量

132

审稿时长

6-12 weeks

期刊介绍： Trends in Pharmacological Sciences (TIPS) is a monthly peer-reviewed reviews journal that focuses on a wide range of topics in pharmacology, pharmacy, pharmaceutics, and toxicology. Launched in 1979, TIPS publishes concise articles discussing the latest advancements in pharmacology and therapeutics research. The journal encourages submissions that align with its core themes while also being open to articles on the biopharma regulatory landscape, science policy and regulation, and bioethics. Each issue of TIPS provides a platform for experts to share their insights and perspectives on the most exciting developments in the field. Through rigorous peer review, the journal ensures the quality and reliability of published articles. Authors are invited to contribute articles that contribute to the understanding of pharmacology and its applications in various domains. Whether it's exploring innovative drug therapies or discussing the ethical considerations of pharmaceutical research, TIPS provides a valuable resource for researchers, practitioners, and policymakers in the pharmacological sciences.