Nanotechnology in bioanalysis: Current trends and applications

IF 3.2

Journal of chromatography open Pub Date : 2025-09-03 DOI:10.1016/j.jcoa.2025.100254

Arshdeep Chopra , Yogindra Kumari , Samarth Kumar , Renuka Sharma , Rohit Bhatia

{"title":"Nanotechnology in bioanalysis: Current trends and applications","authors":"Arshdeep Chopra , Yogindra Kumari , Samarth Kumar , Renuka Sharma , Rohit Bhatia","doi":"10.1016/j.jcoa.2025.100254","DOIUrl":null,"url":null,"abstract":"<div><div>Nanotechnology has evolved into an interdisciplinary trend spanning nearly all scientific domains and has had a profound impact on the global community over the last decade. On the surface, miniaturisation offers mechanical, chemical, and biological components that operate more quickly and affordably. Through the development of new nanoparticles (NPs), nanodevices, nanosensors, and nanosorbents for analytical procedures, the inclusion of nanotechnology has additionally had an impact on bioanalytical sciences. In recent years, numerous studies have been done on the integration of nanomaterials and their analysis in various biological samples. Given the scope of the NPs integrated bioanalysis, the purpose of this review is to provide an overview of multiple types of extraction techniques, sample preparation, and nanomaterials like magnetic NPs, carbon-based NPs, molecularly implanted polymers (MIPs) used in the determination of different drugs in biological specimens, and also to critically evaluate the tools used to examine Green Analytical Chemistry (GAC), such as Green Analytical Procedure Index (GAPI), ComplexGAPI (CoGAPI), Click Analytical Chemistry Index (CACI).</div></div>","PeriodicalId":93576,"journal":{"name":"Journal of chromatography open","volume":"8 ","pages":"Article 100254"},"PeriodicalIF":3.2000,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of chromatography open","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772391725000520","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Nanotechnology has evolved into an interdisciplinary trend spanning nearly all scientific domains and has had a profound impact on the global community over the last decade. On the surface, miniaturisation offers mechanical, chemical, and biological components that operate more quickly and affordably. Through the development of new nanoparticles (NPs), nanodevices, nanosensors, and nanosorbents for analytical procedures, the inclusion of nanotechnology has additionally had an impact on bioanalytical sciences. In recent years, numerous studies have been done on the integration of nanomaterials and their analysis in various biological samples. Given the scope of the NPs integrated bioanalysis, the purpose of this review is to provide an overview of multiple types of extraction techniques, sample preparation, and nanomaterials like magnetic NPs, carbon-based NPs, molecularly implanted polymers (MIPs) used in the determination of different drugs in biological specimens, and also to critically evaluate the tools used to examine Green Analytical Chemistry (GAC), such as Green Analytical Procedure Index (GAPI), ComplexGAPI (CoGAPI), Click Analytical Chemistry Index (CACI).

Abstract Image

查看原文本刊更多论文

纳米技术在生物分析中的应用

纳米技术已经发展成为跨越几乎所有科学领域的跨学科趋势，并在过去十年中对全球社会产生了深远的影响。从表面上看，微型化提供了运行更快、更经济的机械、化学和生物部件。通过开发新的纳米粒子（NPs）、纳米器件、纳米传感器和用于分析程序的纳米吸附剂，纳米技术的应用对生物分析科学产生了额外的影响。近年来，人们对纳米材料的整合及其在各种生物样品中的分析进行了大量的研究。鉴于NPs集成生物分析的范围，本综述的目的是概述多种类型的提取技术，样品制备和纳米材料，如磁性NPs，碳基NPs，分子植入聚合物（MIPs），用于测定生物样品中的不同药物，并批判性地评估用于检验绿色分析化学（GAC）的工具，如绿色分析程序指数（GAPI），络合GAPI (CoGAPI)，单击分析化学指数（CACI）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊