Safety Assessment of Polyquaternium-6 as Used in Cosmetics.

IF 1 4区医学 Q4 PHARMACOLOGY & PHARMACY

International Journal of Toxicology Pub Date : 2025-10-01 Epub Date: 2025-09-11 DOI:10.1177/10915818251361090

Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, David E Cohen, Curtis D Klaassen, Daniel C Liebler, Lisa A Peterson, Ronald C Shank, Thomas J Slaga, Paul W Snyder, Monice M Fiume, Bart Heldreth

引用次数: 0

Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of Polyquaternium-6 as used in cosmetic formulations. This ingredient is reported to function as an antimicrobial agent, antistatic agent, film former, and hair fixative in cosmetics. The Panel cautions that products containing Polyquaternium-6 should be formulated to avoid the formation of nitrosamines. The Panel reviewed data relevant to the safety of this ingredient in cosmetic formulations, and concluded that Polyquaternium-6 is safe in cosmetics in the present practices of use and concentration described in this safety assessment.

查看原文本刊更多论文

聚季铵盐-6在化妆品中的安全性评价。

化妆品成分安全专家小组（专家小组）审查了用于化妆品配方的聚季铵盐-6的安全性。据报道，该成分在化妆品中用作抗菌剂、抗静电剂、成膜剂和头发固定剂。评估小组警告说，含有聚季铵盐-6的产品的配方应避免亚硝胺的形成。评估小组审查了化妆品配方中该成分安全性的相关数据，得出结论认为，在本安全评估中描述的目前使用做法和浓度下，聚季铵-6在化妆品中是安全的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

International Journal of Toxicology 医学-毒理学

CiteScore

3.40

自引率

4.50%

发文量

审稿时长

4.5 months

期刊介绍： The International Journal of Toxicology publishes timely, peer-reviewed papers on current topics important to toxicologists. Six bi-monthly issues cover a wide range of topics, including contemporary issues in toxicology, safety assessments, novel approaches to toxicological testing, mechanisms of toxicity, biomarkers, and risk assessment. The Journal also publishes invited reviews on contemporary topics, and features articles based on symposia. In addition, supplemental issues are routinely published on various special topics, including three supplements devoted to contributions from the Cosmetic Review Expert Panel.