Back Bench Time: The Hidden Factor of Ischemia in Liver Transplantation.

IF 0.8 Q4 SURGERY
Chirurgia Pub Date : 2025-08-01 DOI:10.21614/chirurgia.3168
Alexzandria Karina Khan, Mihnea Ioan Ionescu
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引用次数: 0

Abstract

Ischemia time is a well-established determinant of liver transplant outcomes. Patient survival is substantially affected by prolonged warm (WIT) and cold ischemia time (CIT) of the graft during liver transplant. One component that may be a contributing factor to both WIT and CIT is back bench time (BBT). We have identified BBT as a potentially significant underlying cause of post transplant complications. A literature search was performed using the major available databases. Articles comparing grafts using normothermic machine perfusion and static cold storage with measured WIT and CIT, and post-transplant outcomes, were included. A total of 18 studies were selected; however, we were only able to identify two studies that refer to BBT. In this systematic review, we conclude BBT is a modifiable factor of ischemia that may be impacted by the surgeon experience and requires more in depth studies to fully understand a safe threshold and its effect on post transplant outcomes such as EAD, IC, and graft survival.

静坐时间:肝移植缺血的隐性因素。
缺血时间是肝移植预后的一个公认的决定因素。肝移植过程中,移植物长时间的热缺血(WIT)和冷缺血(CIT)对患者的生存有很大影响。一个可能对WIT和CIT都有贡献的因素是幕后工作时间(BBT)。我们已经确定BBT是移植后并发症的潜在重要潜在原因。使用主要的可用数据库进行文献检索。文章比较了采用恒温机器灌注和静态冷藏的移植物与测量的WIT和CIT,以及移植后的结果。共选取18项研究;然而,我们只能确定两项与BBT有关的研究。在这篇系统综述中,我们得出结论,BBT是一个可改变的缺血因素,可能受到外科医生经验的影响,需要更深入的研究来充分了解安全阈值及其对移植后预后(如EAD, IC和移植物存活)的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Chirurgia
Chirurgia Medicine-Surgery
CiteScore
1.00
自引率
0.00%
发文量
75
审稿时长
4-8 weeks
期刊介绍: Chirurgia is a bimonthly journal. In Chirurgia, original papers in the area of general surgery which neither appeared, nor were sent for publication in other periodicals, can be published. You can send original articles, new surgical techniques, or comprehensive general reports on surgical topics, clinical case presentations and, depending on publication space, - reviews of some articles of general interest to surgeons from other publications. Chirurgia is also a place for sharing information about the activity of various branches of the Romanian Society of Surgery, information on Congresses and Symposiums organized by the Romanian Society of Surgery and participation notes in other scientific meetings. Letters to the editor: Letters commenting on papers published in Chirurgia are welcomed. They should contain substantive ideas and commentaries supported by appropriate data, and should not exceed 2 pages. Please submit these letters to the editor through our online system.
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