Exosomal miR-302b as a novel strategy for reversing cellular senescence and promoting healthy aging.

Abstract

The study by Bi et al. (2025) presents "Senoreverse", an innovative strategy that utilizes exosomal miR-302b to restore the proliferative capacity of senescent cells (SnCs), thus extending lifespan and enhancing cognitive and physical function in aging mice without the risk of tumorigenicity.