Updates to the CASP Infrastructure in 2024.

IF 2.8 4区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Proteins-Structure Function and Bioinformatics Pub Date : 2025-09-01 DOI:10.1002/prot.70042

Andriy Kryshtafovych, Maciej Milostan, Marc F Lensink, Sameer Velankar, Alexandre M J J Bonvin, John Moult, Krzysztof Fidelis

引用次数: 0

Abstract

CASP (critical assessment of structure prediction) conducts community experiments to determine the state of the art in calculating macromolecular structures. The CASP data management system is continually evolving to address the changing needs of the experiments. For CASP16, we expanded the infrastructure to enable data handling of newly introduced categories and fully support pilot categories introduced in CASP15. This technical note also documents the integration of the CASP and CAPRI (Critical Assessment of PRedicted Interactions) systems.

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2024年CASP基础设施的更新。

CASP（结构预测的关键评估）进行社区实验，以确定计算大分子结构的最新技术。CASP数据管理系统不断发展，以满足不断变化的实验需求。对于CASP16，我们扩展了基础设施，使其能够处理新引入的类别，并完全支持CASP15中引入的试点类别。该技术说明还记录了CASP和CAPRI（预测相互作用的关键评估）系统的集成。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Proteins-Structure Function and Bioinformatics 生物-生化与分子生物学

CiteScore

5.90

自引率

3.40%

发文量

172

审稿时长

3 months

期刊介绍： PROTEINS : Structure, Function, and Bioinformatics publishes original reports of significant experimental and analytic research in all areas of protein research: structure, function, computation, genetics, and design. The journal encourages reports that present new experimental or computational approaches for interpreting and understanding data from biophysical chemistry, structural studies of proteins and macromolecular assemblies, alterations of protein structure and function engineered through techniques of molecular biology and genetics, functional analyses under physiologic conditions, as well as the interactions of proteins with receptors, nucleic acids, or other specific ligands or substrates. Research in protein and peptide biochemistry directed toward synthesizing or characterizing molecules that simulate aspects of the activity of proteins, or that act as inhibitors of protein function, is also within the scope of PROTEINS. In addition to full-length reports, short communications (usually not more than 4 printed pages) and prediction reports are welcome. Reviews are typically by invitation; authors are encouraged to submit proposed topics for consideration.