Left Atrial Appendage Characteristics Assessed with Cardiac Computed Tomography in Patients with Atrial Fibrillation and Severe Mitral Valve Disease.

IF 2.8 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Hee Jeong Lee, Jiwon Seo, Kyu Kim, Seo-Yeon Gwak, Iksung Cho, Young Joo Suh, Seung-Hyun Lee, Sak Lee, Geu-Ru Hong, Jong-Won Ha, Young Jin Kim, Chi Young Shim
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Abstract

Purpose: The morphological and functional characteristics and clinical significance of the left atrial appendage (LAA) are well established in patients with non-valvular atrial fibrillation (AF). However, data on the LAA characteristics in patients with mitral valve (MV) disease are limited. This study aimed to identify the LAA characteristics in AF patients with severe MV disease.

Materials and methods: A total of 506 AF patients who underwent cardiac computed tomography (CT) as preoperative evaluations for MV surgery were retrospectively analyzed. The prevalences of different LAA morphologies (cactus, cauliflower, windsock, chicken wing), LAA ostium diameter, LAA volume, and LAA flow stasis or thrombus were assessed. The LAA variables were compared according to the predominant MV dysfunction.

Results: The most common LAA morphology was cactus (n=211, 41.7%), followed by cauliflower (n=143, 28.3%), windsock (n=90, 17.8%), and chicken wing (n=60, 11.9%). The average LAA ostium maximal diameter and LAA volume were 35.3±8.0 mm and 22.1±15.1 mL, respectively. LAA stasis was found in 215 patients (42.5%) and LAA thrombus in 93 patients (18.4%). Patients with mitral stenosis predominance showed significantly smaller LAA volume compared to those with mitral regurgitation predominance (17.8±11.7 mL vs. 26.9±16.8 mL, p<0.001). However, LAA flow stasis [190 (71.7%) vs. 25 (10.4%), p<0.001] and thrombus [89 (33.6%) vs. 4 (1.7%), p<0.001] were remarkably prevalent in these patients.

Conclusion: Due to advanced LAA remodeling in AF patients with severe MV disease, the morphologic distribution of LAA types differs from that established in patients without MV disease.

Abstract Image

Abstract Image

Abstract Image

心房颤动合并严重二尖瓣疾病患者左心耳ct特征评估
目的:了解非瓣膜性心房颤动(AF)患者左心耳(LAA)的形态、功能特征及临床意义。然而,关于二尖瓣疾病患者LAA特征的数据有限。本研究旨在确定AF合并严重MV疾病患者LAA的特征。材料和方法:回顾性分析506例房颤患者行心脏计算机断层扫描(CT)作为MV手术术前评估。评估不同LAA形态(仙人掌、花椰菜、风袜子、鸡翅)、LAA口直径、LAA体积、LAA血流停滞或血栓的患病率。根据主要的MV功能障碍比较LAA变量。结果:最常见的LAA形态为仙人掌(211例,41.7%),其次为菜花(143例,28.3%)、风袋(90例,17.8%)和鸡翅(60例,11.9%)。LAA的平均最大直径为35.3±8.0 mm, LAA容积为22.1±15.1 mL。LAA停滞215例(42.5%),LAA血栓93例(18.4%)。二尖瓣狭窄优势组LAA体积明显小于二尖瓣反流优势组(17.8±11.7 mL vs. 26.9±16.8 mL)。结论:房颤伴重度中压病变患者LAA重构进展,LAA类型形态分布与无中压病变患者存在差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Yonsei Medical Journal
Yonsei Medical Journal 医学-医学:内科
CiteScore
4.50
自引率
0.00%
发文量
167
审稿时长
3 months
期刊介绍: The goal of the Yonsei Medical Journal (YMJ) is to publish high quality manuscripts dedicated to clinical or basic research. Any authors affiliated with an accredited biomedical institution may submit manuscripts of original articles, review articles, case reports, brief communications, and letters to the Editor.
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