[Expression of Concern] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells.

IF 3.9 3区 医学 Q2 ONCOLOGY
Oncology reports Pub Date : 2025-11-01 Epub Date: 2025-08-29 DOI:10.3892/or.2025.8979
Chunlan Tang, Eunsil Hahm, Seyeon Bae, Jae Seung Kang, Wang Jae Lee
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引用次数: 0

Abstract

Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the immunohistochemical images shown in Figs. 1E and 5E appeared to show an overlapping section, even though Figs. 1 and 5 were intended to show the results of SHP2 and Ras expression experiments, respectively. The authors were contacted by the Editorial Office to offer an explanation for this apparent anomaly in the presentation of the data in this paper; however, up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. [Oncology Reports 39: 611‑618, 2018; DOI: 10.3892/or.2017.6109].

Src同源磷酸化酪氨酸磷酸酶2通过抑制肺癌细胞凋亡和激活Ras/PI3K/Akt1/survivin通路介导顺铂相关耐药。
在本文发表后,一位关心的读者引起了编辑的注意,尽管图1和图5分别是SHP2和Ras表达实验的结果,但图1E和图5E所示的免疫组化图像似乎显示了重叠的切片。编辑部联系了作者,要求他们对这篇论文中数据呈现的明显异常作出解释;然而,到目前为止,他们还没有任何回应。由于编辑部已经意识到围绕本文科学完整性的潜在问题,在编辑部继续进一步调查此事的同时,我们发出一份关注表达,通知读者这一潜在问题。[肿瘤杂志]39:611‑618,2018;DOI: 10.3892 / or.2017.6109]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Oncology reports
Oncology reports 医学-肿瘤学
CiteScore
8.50
自引率
2.40%
发文量
187
审稿时长
3 months
期刊介绍: Oncology Reports is a monthly, peer-reviewed journal devoted to the publication of high quality original studies and reviews concerning a broad and comprehensive view of fundamental and applied research in oncology, focusing on carcinogenesis, metastasis and epidemiology.
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