[Retracted] Sevoflurane attenuates brain damage through inhibiting autophagy and apoptosis in cerebral ischemia‑reperfusion rats.

IF 3.5 3区 医学 Q2 MEDICINE, RESEARCH & EXPERIMENTAL
Molecular medicine reports Pub Date : 2025-11-01 Epub Date: 2025-08-24 DOI:10.3892/mmr.2025.13656
Cun-Xian Shi, Jin Jin, Xue-Qin Wang, Teng Song, Guang-Hong Li, Ke-Zhong Li, Jia-Hai Ma
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引用次数: 0

Abstract

Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that, regarding the immunohistochemistry experiments shown in Fig. 4A, the 'Tak‑242' and the 'Se+Tak‑242' panels appeared to show an overlapping section of data, and for the western blot data shown in Figs. 6 and 7, the β‑actin data in Fig. 6A were strikingly similar to the NF‑κB data in Fig. 7A, such that data which were intended to show the results from differently performed experiments had apparently been derived from the same original sources. Following an independent analysis of the data in the Editorial Office, a small overlapping section of data was also identified comparing the 'Tak‑242' and 'Se' panels for the cellular morphological images in Fig. 5A, and the western blots featured in Fig. 6A were found to have subsequently reappeared in a paper written by different authors at different research institutes in the journal Drug Design, Development and Therapy. In view of the various instances of data duplication identified in this paper, and the reappearance of certain of the data in a subsequent article, the Editor of Molecular Medicine Reports has decided that this paper should be retracted from the Journal on account of a lack of confidence in the presented data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused. [Molecular Medicine Reports 21: 123‑130, 2020; DOI: 10.3892/mmr.2019.10832].

【回缩】七氟醚通过抑制脑缺血再灌注大鼠自噬和细胞凋亡减轻脑损伤。
在本文发表后,一位关心的读者提请编辑注意,在图4A所示的免疫组织化学实验中,“Tak - 242”和“Se+Tak - 242”板似乎显示了重叠的数据部分,而对于图6和7所示的western blot数据,图6A中的β - actin数据与图7A中的NF - κB数据惊人地相似。因此,用来显示不同实验结果的数据显然来自相同的原始来源。在对编辑部的数据进行独立分析后,还发现了一小部分重叠的数据,将图5A中的细胞形态学图像的“Tak - 242”和“Se”面板进行比较,发现图6A中的western blots随后在不同研究机构的不同作者撰写的论文中重新出现在《药物设计,开发和治疗》杂志上。鉴于本文中发现的各种数据重复情况,以及在随后的文章中重复出现的某些数据,《分子医学报告》的编辑决定,由于对所呈现的数据缺乏信心,应从该杂志撤回这篇论文。作者被要求对这些问题作出解释,但编辑部没有收到令人满意的答复。对于由此给读者带来的不便,本刊编辑深表歉意。[分子医学报告]21:123‑130,2020;DOI: 10.3892 / mmr.2019.10832]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Molecular medicine reports
Molecular medicine reports 医学-病理学
CiteScore
7.60
自引率
0.00%
发文量
321
审稿时长
1.5 months
期刊介绍: Molecular Medicine Reports is a monthly, peer-reviewed journal available in print and online, that includes studies devoted to molecular medicine, underscoring aspects including pharmacology, pathology, genetics, neurosciences, infectious diseases, molecular cardiology and molecular surgery. In vitro and in vivo studies of experimental model systems pertaining to the mechanisms of a variety of diseases offer researchers the necessary tools and knowledge with which to aid the diagnosis and treatment of human diseases.
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