{"title":"Challenges in diagnosis of cardiac sarcoidosis-an observational study from tertiary care center in north India.","authors":"Asharam Panda, Sumit Kumar, Nitish Naik","doi":"10.1016/j.ihj.2025.08.003","DOIUrl":null,"url":null,"abstract":"<p><p>This retrospective observational study was conducted in a tertiary care hospital to assess the challenges involved in the diagnosis of cardiac sarcoidosis. The study included a total of 42 patients with primary cardiac manifestation of sarcoidosis and imaging evidence of patchy myocardial inflammation. Ventricular tachycardia(20) was the most common cardiac manifestation, followed by heart failure(12) and complete heart block(10). Histopathological evidence of sarcoidosis was found only in 12 patients (one endocardial biopsy, 11 extracardiac source). We could not find evidence of extracardiac involvement in the majority of patients. As the diagnostic criteria mainly stress upon the evidence of extracardiac sarcoidosis, diagnosis remains uncertain in many patients.</p>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":1.8000,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian heart journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.ihj.2025.08.003","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
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Abstract
This retrospective observational study was conducted in a tertiary care hospital to assess the challenges involved in the diagnosis of cardiac sarcoidosis. The study included a total of 42 patients with primary cardiac manifestation of sarcoidosis and imaging evidence of patchy myocardial inflammation. Ventricular tachycardia(20) was the most common cardiac manifestation, followed by heart failure(12) and complete heart block(10). Histopathological evidence of sarcoidosis was found only in 12 patients (one endocardial biopsy, 11 extracardiac source). We could not find evidence of extracardiac involvement in the majority of patients. As the diagnostic criteria mainly stress upon the evidence of extracardiac sarcoidosis, diagnosis remains uncertain in many patients.
期刊介绍：
Indian Heart Journal (IHJ) is the official peer-reviewed open access journal of Cardiological Society of India and accepts articles for publication from across the globe. The journal aims to promote high quality research and serve as a platform for dissemination of scientific information in cardiology with particular focus on South Asia. The journal aims to publish cutting edge research in the field of clinical as well as non-clinical cardiology - including cardiovascular medicine and surgery. Some of the topics covered are Heart Failure, Coronary Artery Disease, Hypertension, Interventional Cardiology, Cardiac Surgery, Valvular Heart Disease, Pulmonary Hypertension and Infective Endocarditis. IHJ open access invites original research articles, research briefs, perspective, case reports, case vignette, cardiovascular images, cardiovascular graphics, research letters, correspondence, reader forum, and interesting photographs, for publication. IHJ open access also publishes theme-based special issues and abstracts of papers presented at the annual conference of the Cardiological Society of India.
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