Resistant hypertension treated with laparoscopic-assisted renal denervation in a patient with end-stage renal disease: a case report.

IF 0.8 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

European Heart Journal: Case Reports Pub Date : 2025-08-12 eCollection Date: 2025-08-01 DOI:10.1093/ehjcr/ytaf387

Jiapeng Chu, Xiaolong Liu, Chunlai Shao

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Abstract

Background: In patients with end-stage renal disease (ESRD) on dialysis, hypertension is commonly detected and inadequately controlled despite the use of multiple anti-hypertensive medications. Sympathetic hyperactivation is a key feature in chronic kidney disease and can be targeted by renal denervation (RDN).

Case summary: A 47-year-old male patient with pharmacologically resistant hypertension and ESRD on peritoneal dialysis underwent radiofrequency renal nerve ablation using a laparoscopic-assisted system. During the 6-month follow-up after the operation, we observed a remarkable and sustained reduction in blood pressure, with a significant decrease in oral anti-hypertensive medications.

Discussion: This case demonstrates the safety and effectiveness of laparoscopic-assisted RDN for lowering blood pressure. This technology, as an alternative to catheter-based RDN, bears the potential for wider application in high-risk patients with severe renal failure.

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腹腔镜辅助肾去神经术治疗顽固性高血压终末期肾病1例

背景：在终末期肾病（ESRD）透析患者中，尽管使用了多种降压药物，但高血压通常被发现且控制不充分。交感神经过度激活是慢性肾脏疾病的一个关键特征，可以通过肾去神经支配（RDN）治疗。病例总结：一位47岁的男性患者，患有药物抵抗性高血压和腹膜透析的ESRD，采用腹腔镜辅助系统进行射频肾神经消融。在术后6个月的随访中，我们观察到患者血压持续显著下降，口服降压药用量显著减少。讨论：本病例证明腹腔镜辅助RDN降血压的安全性和有效性。该技术作为基于导管的RDN的替代方案，在严重肾功能衰竭的高危患者中具有更广泛的应用潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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