A Review on the Evolving Role of Radiation Therapy in the Treatment of Locally Advanced Rectal Cancer.

IF 3.4 4区 医学 Q2 ONCOLOGY
Zeinab Dandash, Tala Mobayed, Sally Temraz, Ali Shamseddine, Samer Doughan, Samer Deeba, Zeina Ayoub, Toufic Eid, Bassem Youssef, Lara Hilal
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引用次数: 0

Abstract

Treatment of locally advanced rectal cancer (LARC), clinical stages II-III, typically involves multimodal treatment options. Over the past decade, the role of radiation therapy as a neoadjuvant treatment for LARC has evolved and is currently a part of total neoadjuvant therapy (TNT). Some recently published studies advocate for the omission of radiation therapy entirely, while others report on a non-operative approach that emphasizes the use of higher radiation therapy doses. This review aims to evaluate the latest literature on the current role of radiation therapy in the management of LARC, with a discussion of how to best select the most appropriate treatment protocol based on individual patient and tumor characteristics, comorbidities, and personal needs and preferences.

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放射治疗在局部晚期直肠癌治疗中的作用
治疗局部晚期直肠癌(LARC),临床阶段II-III,通常涉及多模式治疗方案。在过去的十年中,放射治疗作为LARC的新辅助治疗的作用不断发展,目前是总新辅助治疗(TNT)的一部分。最近发表的一些研究主张完全省略放射治疗,而另一些研究则报告了一种非手术方法,强调使用更高的放射治疗剂量。本综述旨在评估目前放射治疗在LARC治疗中的作用的最新文献,并讨论如何根据个体患者和肿瘤特征、合并症以及个人需求和偏好来选择最合适的治疗方案。
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来源期刊
Current oncology
Current oncology ONCOLOGY-
CiteScore
3.30
自引率
7.70%
发文量
664
审稿时长
1 months
期刊介绍: Current Oncology is a peer-reviewed, Canadian-based and internationally respected journal. Current Oncology represents a multidisciplinary medium encompassing health care workers in the field of cancer therapy in Canada to report upon and to review progress in the management of this disease. We encourage submissions from all fields of cancer medicine, including radiation oncology, surgical oncology, medical oncology, pediatric oncology, pathology, and cancer rehabilitation and survivorship. Articles published in the journal typically contain information that is relevant directly to clinical oncology practice, and have clear potential for application to the current or future practice of cancer medicine.
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