EXPRESSION OF CONCERN: Discovery of a Novel Viroid-Like Circular RNA in Colorectal Cancer

IF 24.9 1区 医学 Q1 ONCOLOGY
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引用次数: 0

Abstract

Wu M, Li W, Hu N, Liu C, Li J, Li Y, et al. Discovery of a Novel Viroid-Like Circular RNA in Colorectal Cancer. Cancer Commun. 2025;45(1):46-50. doi: 10.1002/cac2.12626.

This Expression of Concern is for the above article, published online on 09 November 2024 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editor-in-Chief, Rui-Hua Xu; Sun Yat-sen University Cancer Center; and John Wiley & Sons Australia. The Expression of Concern has been agreed upon following information provided by a third party regarding the identification of the CRC-associated viroid. The authors reported this viroid-like circRNA as absent from the human genome based on the hg38 reference. However, the sequence is present at chromosome13:96543662-96543775 in the more complete T2T human genome reference, indicating it is not an exogenous RNA element. The authors have acknowledged the need for further investigation, particularly in light of the discrepancies from the difference between the hg38 and T2T human genomes. The editors have decided to issue this Expression of Concern to alert readers as further investigations proceed.

Abstract Image

关注表达:在结直肠癌中发现一种新的类病毒环状RNA。
吴敏,李伟,胡宁,刘超,李军,李勇,等。结直肠癌中一种新型类病毒环状RNA的发现。中华癌症杂志。2025;45(1):46-50。doi: 10.1002 / cac2.12626。上述文章于2024年11月9日在线发表在Wiley在线图书馆(wileyonlinelibrary.com)上,经期刊主编徐瑞华同意发布。中山大学肿瘤中心;和John Wiley &; Sons Australia。关注表达已就以下由第三方提供的关于crc相关类病毒鉴定的信息达成一致。作者报告了基于hg38参考的人类基因组中不存在这种类病毒circRNA。然而,在更完整的T2T人类基因组参考中,该序列存在于染色体13:96543662-96543775,表明它不是外源RNA元件。作者承认需要进一步调查,特别是考虑到hg38和T2T人类基因组之间的差异。编辑们决定在进一步的调查进行时发布这一关注表达,以提醒读者。
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来源期刊
Cancer Communications
Cancer Communications Biochemistry, Genetics and Molecular Biology-Cancer Research
CiteScore
25.50
自引率
4.30%
发文量
153
审稿时长
4 weeks
期刊介绍: Cancer Communications is an open access, peer-reviewed online journal that encompasses basic, clinical, and translational cancer research. The journal welcomes submissions concerning clinical trials, epidemiology, molecular and cellular biology, and genetics.
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