Marta Freixas Bermejo, Luis Riera Soler, Laura García Martínez, Oscar Segarra Cantón
{"title":"Recurrent Pneumothorax in a Pediatric Patient with Crohn's Disease Receiving Ustekinumab Treatment: Case Report.","authors":"Marta Freixas Bermejo, Luis Riera Soler, Laura García Martínez, Oscar Segarra Cantón","doi":"10.1159/000543991","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>We present the case of a patient with Crohn's disease who experienced recurrent pneumothorax after starting treatment with ustekinumab.</p><p><strong>Case presentation: </strong>A patient with Crohn's disease started an induction regimen with intravenous ustekinumab, and 2 months later he presented a left-sided pneumothorax. It had an atypical evolution that required surgical management. The medication was withdrawn and the pneumothorax resolved completely. One year later, he had a new flare-up of Crohn's disease and ustekinumab therapy was restarted, presenting a new episode of pneumothorax.</p><p><strong>Conclusion: </strong>To our knowledge, this is the first report of recurrent pneumothorax following two separate attempts to initiate ustekinumab.</p>","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"134-139"},"PeriodicalIF":0.6000,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882160/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Gastroenterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000543991","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: We present the case of a patient with Crohn's disease who experienced recurrent pneumothorax after starting treatment with ustekinumab.
Case presentation: A patient with Crohn's disease started an induction regimen with intravenous ustekinumab, and 2 months later he presented a left-sided pneumothorax. It had an atypical evolution that required surgical management. The medication was withdrawn and the pneumothorax resolved completely. One year later, he had a new flare-up of Crohn's disease and ustekinumab therapy was restarted, presenting a new episode of pneumothorax.
Conclusion: To our knowledge, this is the first report of recurrent pneumothorax following two separate attempts to initiate ustekinumab.