Effect of Potentilla anserina L. Extract on the Activity of Oxidative and Hydrolytic Enzymes in Blood Cells of Rats under Induced Stress.

IF 0.6 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

Bulletin of Experimental Biology and Medicine Pub Date : 2025-06-01 Epub Date: 2025-08-28 DOI:10.1007/s10517-025-06456-1

E E Saveleva, N A Bulgakova, O F Veselova, M V Dolgushin

引用次数: 0

Abstract

We studied the effect of thick extract of Potentilla anserina L. on activities of antioxidant defense system enzymes in rat blood under conditions of induced stress. Antioxidant properties of the extract were preliminarily assessed by the reaction with 2,2-diphenyl-1-picrylhydrazyl. Stress in animals was induced by forced swimming; the extract was administered preventively orally over 10 days. Preventive use of the extract in aqueous suspension produced an appreciable effect on stress-induced oxidative processes in neutrophils and lymphocytes. The extract acts as an acceptor of free radicals and has a positive effect on the adaptive mechanisms of the body under conditions of physiological response to an unfavorable situation.

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蕨麻提取物对应激大鼠血细胞氧化酶和水解酶活性的影响。

研究了蕨麻粗提物在诱导应激条件下对大鼠血液抗氧化防御系统酶活性的影响。通过与2,2-二苯基-1-苦味酰肼的反应，初步评价了提取物的抗氧化性能。强迫游泳诱导动物应激；该提取物被预防性口服超过10天。水悬浮液中提取物的预防性使用对中性粒细胞和淋巴细胞的应激诱导氧化过程产生了明显的影响。该提取物作为自由基的受体，在机体对不利情况的生理反应条件下，对机体的适应机制有积极作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bulletin of Experimental Biology and Medicine 医学-医学：研究与实验

CiteScore

1.50

自引率

14.30%

发文量

265

审稿时长

2 months

期刊介绍： Bulletin of Experimental Biology and Medicine presents original peer reviewed research papers and brief reports on priority new research results in physiology, biochemistry, biophysics, pharmacology, immunology, microbiology, genetics, oncology, etc. Novel trends in science are covered in new sections of the journal - Biogerontology and Human Ecology - that first appeared in 2005. World scientific interest in stem cells prompted inclusion into Bulletin of Experimental Biology and Medicine a quarterly scientific journal Cell Technologies in Biology and Medicine (a new Russian Academy of Medical Sciences publication since 2005). It publishes only original papers from the leading research institutions on molecular biology of stem and progenitor cells, stem cell as the basis of gene therapy, molecular language of cell-to-cell communication, cytokines, chemokines, growth and other factors, pilot projects on clinical use of stem and progenitor cells. The Russian Volume Year is published in English from April.