Pancreatic Metastasis From a Vulvar Melanoma Diagnosed by Endoscopic Ultrasound-Guided Fine-Needle Biopsy.

IF 0.5 Q4 GASTROENTEROLOGY & HEPATOLOGY
ACG Case Reports Journal Pub Date : 2025-08-21 eCollection Date: 2025-08-01 DOI:10.14309/crj.0000000000001784
Ricardo Almeida, Luiza Bicudo, Leika Felipe, Gustavo Andrade de Paulo, Fauze Maluf-Filho, Luciano Lenz
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引用次数: 0

Abstract

Vulvar melanoma (VM) is a rare and aggressive malignancy with a high metastatic potential. We present the case of an 82-year-old woman who initially presented with vaginal bleeding and was diagnosed with VM with lymph node involvement. Despite surgical and palliative interventions, she later developed brain, nodal, and pancreatic metastases. Endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) confirmed pancreatic metastasis through immunohistochemistry. To our knowledge, this is the first reported case of pancreatic metastasis from VM diagnosed by EUS-FNB. This case highlights the importance of EUS-FNB in diagnosing metastatic lesions in unusual locations.

Abstract Image

Abstract Image

Abstract Image

超声内镜引导下细针活检诊断外阴黑色素瘤胰腺转移。
外阴黑色素瘤(VM)是一种罕见的侵袭性恶性肿瘤,具有很高的转移潜力。我们提出一个82岁的妇女谁最初提出阴道出血,并被诊断为VM与淋巴结累及的情况下。尽管进行了手术和姑息治疗,她后来还是出现了脑、淋巴结和胰腺转移。内镜超声引导下细针活检(EUS-FNB)经免疫组化证实胰腺转移。据我们所知,这是第一例用EUS-FNB诊断的VM胰腺转移病例。本病例强调了EUS-FNB在诊断异常部位转移性病变中的重要性。
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来源期刊
ACG Case Reports Journal
ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-
自引率
14.30%
发文量
170
审稿时长
12 weeks
期刊介绍: ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.
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