Stingless bee propolis: a comprehensive review of chemical constituents and health efficacy

IF 4.9 3区 化学 Q1 CHEMISTRY, MEDICINAL
Nosiba A. Alsarayrah, Rafeezul Mohamed, Eshaifol A. Omar
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Abstract

Propolis, consisting of plant-derived materials, wax, and bee secretions, is abundant in bioactive constituents like flavonoids, phenolic compounds, and terpenes, which enhance its various biological functions. These encompass antioxidant, anti-inflammatory, antibacterial, anticancer, antidiabetic, and immunomodulatory properties. Propolis has demonstrated effectiveness in the prevention and treatment of multiple illnesses, including cardiovascular disease, atherosclerosis, infections, diabetes, wound healing, and burns. Its extensive health benefits endorse its application in medications, nutritional supplements, and cosmetics, where it is acknowledged as a safe and efficacious natural product. Propolis, whether utilized in its raw state, as extracts, or in conjunction with other products, exhibits considerable promise in alternative medicine and nutritional health. Propolis extracts are crucial to examine as a key component in health and wellness, offering prospective applications in disease prevention and therapeutic support Further research is necessary to clarify its molecular mechanisms, examine potential allergic reactions, and determine ideal dosages for various ages. This article provides a comprehensive comparative examination of various propolis types, emphasizing their distinct phytochemical contents and varying biological effects concurrently. It integrates results from both in vitro and in vivo investigations, enhancing the comprehension of health applications and mechanisms of action, grounded comparisons in pertinent prior studies.

Graphical Abstract

无刺蜂胶:化学成分及保健功效综述
蜂胶由植物源性材料、蜂蜡和蜜蜂分泌物组成,含有丰富的类黄酮、酚类化合物和萜烯等生物活性成分,增强了蜂胶的各种生物功能。这些包括抗氧化、抗炎、抗菌、抗癌、抗糖尿病和免疫调节特性。蜂胶在预防和治疗多种疾病方面已被证明有效,包括心血管疾病、动脉粥样硬化、感染、糖尿病、伤口愈合和烧伤。其广泛的健康益处支持其在药物,营养补充剂和化妆品中的应用,在这些领域,它被公认为是一种安全有效的天然产品。蜂胶,无论是以其原始状态,作为提取物,还是与其他产品结合使用,在替代医学和营养健康方面都显示出相当大的前景。蜂胶提取物作为保健和保健的关键成分,在疾病预防和治疗支持方面提供了潜在的应用前景,需要进一步研究阐明其分子机制,检查潜在的过敏反应,并确定不同年龄的理想剂量。本文对不同类型的蜂胶进行了全面的比较研究,强调了它们不同的植物化学成分和不同的生物效应。它整合了体外和体内研究的结果,增强了对健康应用和作用机制的理解,并在相关先前研究的基础上进行了比较。图形抽象
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来源期刊
Natural Products and Bioprospecting
Natural Products and Bioprospecting CHEMISTRY, MEDICINAL-
CiteScore
8.30
自引率
2.10%
发文量
39
审稿时长
13 weeks
期刊介绍: Natural Products and Bioprospecting serves as an international forum for essential research on natural products and focuses on, but is not limited to, the following aspects: Natural products: isolation and structure elucidation Natural products: synthesis Biological evaluation of biologically active natural products Bioorganic and medicinal chemistry Biosynthesis and microbiological transformation Fermentation and plant tissue cultures Bioprospecting of natural products from natural resources All research articles published in this journal have undergone rigorous peer review. In addition to original research articles, Natural Products and Bioprospecting publishes reviews and short communications, aiming to rapidly disseminate the research results of timely interest, and comprehensive reviews of emerging topics in all the areas of natural products. It is also an open access journal, which provides free access to its articles to anyone, anywhere.
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