Synthesis of phenazine-1,6-diyldimethanol, a natural product from Brevibacteria

IF 1.5 4区化学 Q3 CHEMISTRY, ORGANIC

Tetrahedron Letters Pub Date : 2025-09-02 DOI:10.1016/j.tetlet.2025.155802

Ramsha Iftikhar , Mohan Bhadbhade , Ruoming Tian , Giancarlo Pascali , Roger Read , Luke Hunter

引用次数: 0

Abstract

A concise total synthesis of the C2-symmetric marine alkaloid, phenazine-1,6-diyldimethanol, is reported. X-ray crystal structures for three phenazine derivatives are presented, and a simple and general NMR-based method for distinguishing 1,6- from 1,9-disubstituted phenazines is described.

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短毛杆菌天然产物非那嗪-1,6-二基二甲醇的合成

报道了c2对称海洋生物碱吩那嗪-1,6-二基二甲醇的简明全合成。介绍了三种非那嗪衍生物的x射线晶体结构，并描述了一种简单而通用的基于核磁共振的方法来区分1,6-和1,9-二取代非那嗪。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tetrahedron Letters 化学-有机化学

CiteScore

3.50

自引率

5.60%

发文量

521

审稿时长

28 days

期刊介绍： Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.