Non-coding RNAs as key player in cancer diagnosis and treatment

IF 2.3 4区生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

FEBS Open Bio Pub Date : 2025-09-01 DOI:10.1002/2211-5463.70088

Marcin Majka

引用次数: 0

Abstract

Most of the human genome is transcribed into noncoding RNAs (ncRNAs), which although do not encode proteins, are often involved in key cellular processes. Recent technological advances have accelerated the discovery of ncRNA as well as our understanding of ncRNAs as cancer biomarkers and targets. In this “In the Limelight” special issue of FEBS Open Bio, four review articles by leading experts provide an overview of the role of ncRNAs in cancer, from their association to liver cancer to their role as oncogenes in head and neck squamous cell carcinoma (HNSCC).

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非编码rna在癌症诊断和治疗中的关键作用

大多数人类基因组被转录成非编码rna (ncRNAs)，虽然不编码蛋白质，但通常参与关键的细胞过程。最近的技术进步加速了ncRNA的发现，以及我们对ncRNA作为癌症生物标志物和靶点的理解。在这一期《FEBS Open Bio》的“In the Limelight”特刊中，由权威专家撰写的四篇综述文章概述了ncRNAs在癌症中的作用，从它们与肝癌的关系到它们在头颈部鳞状细胞癌（HNSCC）中的致癌基因作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

FEBS Open Bio BIOCHEMISTRY & MOLECULAR BIOLOGY-

CiteScore

5.10

自引率

0.00%

发文量

173

审稿时长

10 weeks

期刊介绍： FEBS Open Bio is an online-only open access journal for the rapid publication of research articles in molecular and cellular life sciences in both health and disease. The journal''s peer review process focuses on the technical soundness of papers, leaving the assessment of their impact and importance to the scientific community. FEBS Open Bio is owned by the Federation of European Biochemical Societies (FEBS), a not-for-profit organization, and is published on behalf of FEBS by FEBS Press and Wiley. Any income from the journal will be used to support scientists through fellowships, courses, travel grants, prizes and other FEBS initiatives.