Pengxiang Guo, Hongliang Xu, Wanjie Zhang, Yuhao Shi, Wensheng Xiang, Fengshan Yang
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{"title":"Recent advances in the pesticide activities of chalcone derivatives","authors":"Pengxiang Guo, Hongliang Xu, Wanjie Zhang, Yuhao Shi, Wensheng Xiang, Fengshan Yang","doi":"10.1002/ps.70179","DOIUrl":null,"url":null,"abstract":"Obtaining pesticide‐active structures from natural resources and using them as lead compounds for the invention of new pesticides has become a popular research trend in the field of pesticide science in recent years. Chalcone is a simple scaffold for a number of natural compounds and is extensively found in plants. Due to the presence of active α, β‐unsaturated carbonyl groups, chalcone and its derivatives display a wide array of biological activities. Chemically, chalcone can be modified and synthesized easily to produce a variety of compounds with different structures. It is these properties that render chalcone analogs an effective tool for modifying the biological activity of pesticide molecules. This paper synthesizes the relevant research reports and patents of chalcone compounds with pesticide activity in the past 20 years. By summarizing the past research as well as combining the current development trend, we focus on five future directions of chalcone development, aiming to provide an effective reference value for the research of chalcone structure in pesticides. © 2025 Society of Chemical Industry.","PeriodicalId":218,"journal":{"name":"Pest Management Science","volume":"56 1","pages":""},"PeriodicalIF":3.8000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pest Management Science","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1002/ps.70179","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"AGRONOMY","Score":null,"Total":0}
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查尔酮衍生物农药活性研究进展
从自然资源中获取具有农药活性的结构,并将其作为先导化合物用于新农药的发明已成为近年来农药科学领域的一个热门研究方向。查尔酮是许多天然化合物的简单支架,广泛存在于植物中。由于活性α, β‐不饱和羰基的存在,查尔酮及其衍生物显示出广泛的生物活性。在化学上,查尔酮可以很容易地被修饰和合成,以产生各种不同结构的化合物。正是这些特性使查尔酮类似物成为修饰农药分子生物活性的有效工具。本文对近20年来查尔酮类具有农药活性化合物的相关研究报告和专利进行了综述。通过总结过去的研究并结合当前的发展趋势,我们重点探讨了查尔酮未来的五个发展方向,旨在为农药中查尔酮结构的研究提供有效的参考价值。©2025化学工业协会。
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