Multifocal Colonic Masses as a Presentation of Secondary Extramedullary Plasmacytoma in Relapsing-Refractory Multiple Myeloma: A Case Report and Review of Literature

IF 1.5 Q3 GASTROENTEROLOGY & HEPATOLOGY

JGH Open Pub Date : 2025-08-29 DOI:10.1002/jgh3.70239

Sirisha Gaddipati, Sunny Sandhu, Eric F. Martin

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Abstract

Background

Multiple myeloma (MM) is a common plasma cell malignancy; however, extramedullary multiple myeloma (EMM) is an aggressive phenotype in which malignant plasma cells proliferate outside of the bone marrow.

Aims

Extramedullary plasmacytomas (EMP) are uncommon and gastrointestinal involvement is exceedingly rare.

Case Presentation

Here, we present a case of multifocal secondary colonic EMP in a patient with relapsed refractory multiple myeloma (RRMM) and review literature demonstrating other cases of secondary colonic EMP.

Abstract Image

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复发难治性多发性骨髓瘤继发髓外浆细胞瘤的多灶性结肠肿块一例报告及文献复习

多发性骨髓瘤（MM）是一种常见的浆细胞恶性肿瘤；然而，髓外多发性骨髓瘤（EMM）是一种侵袭性表型，其中恶性浆细胞在骨髓外增殖。目的髓外浆细胞瘤（EMP）是一种罕见的疾病，其累及胃肠道的病例极为罕见。在此，我们报告一例复发性难治性多发性骨髓瘤（RRMM）患者的多灶性继发性结肠EMP，并回顾其他继发性结肠EMP病例的文献。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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