Patient-reported outcome measures add value as clinical trial endpoints

IF 50 1区医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Nature Medicine Pub Date : 2025-08-25 DOI:10.1038/s41591-025-03906-1

Norah L. Crossnohere, Anne L. R. Schuster, Jeffrey Bruckel, Ronald C. Chen, Amy M. Cizik, Samantha Cruz Rivera, Christopher Muth, Linda Nelsen, Derek Kyte, Albert W. Wu, Elissa Thorner, Claire Snyder, Michael Brundage

引用次数: 0

Abstract

Asking patients about their symptoms, functioning and well-being during clinical trials can influence trial outcomes, regulatory decisions and clinical practice.

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患者报告的结果测量作为临床试验终点增加了价值

在临床试验期间询问患者的症状、功能和健康状况会影响试验结果、监管决定和临床实践。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Medicine 医学-生化与分子生物学

CiteScore

100.90

自引率

0.70%

发文量

525

审稿时长

1 months

期刊介绍： Nature Medicine is a monthly journal publishing original peer-reviewed research in all areas of medicine. The publication focuses on originality, timeliness, interdisciplinary interest, and the impact on improving human health. In addition to research articles, Nature Medicine also publishes commissioned content such as News, Reviews, and Perspectives. This content aims to provide context for the latest advances in translational and clinical research, reaching a wide audience of M.D. and Ph.D. readers. All editorial decisions for the journal are made by a team of full-time professional editors. Nature Medicine consider all types of clinical research, including: -Case-reports and small case series -Clinical trials, whether phase 1, 2, 3 or 4 -Observational studies -Meta-analyses -Biomarker studies -Public and global health studies Nature Medicine is also committed to facilitating communication between translational and clinical researchers. As such, we consider “hybrid” studies with preclinical and translational findings reported alongside data from clinical studies.