{"title":"Prozone Effect of the AQP4-IgG Test in a Patient With NMOSD","authors":"Jianwei Lou, Lili Cao, Kunqian Ji","doi":"10.1001/jamaneurol.2025.2918","DOIUrl":null,"url":null,"abstract":"This case report describes a false-negative result of the aquaporin-4–immunoglobulin G (AQP4-IgG) test due to the prozone effect in a woman with neuromyelitis optica spectrum disorder (NMOSD).","PeriodicalId":14677,"journal":{"name":"JAMA neurology","volume":"24 1","pages":""},"PeriodicalIF":21.3000,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JAMA neurology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1001/jamaneurol.2025.2918","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
This case report describes a false-negative result of the aquaporin-4–immunoglobulin G (AQP4-IgG) test due to the prozone effect in a woman with neuromyelitis optica spectrum disorder (NMOSD).
期刊介绍:
JAMA Neurology is an international peer-reviewed journal for physicians caring for people with neurologic disorders and those interested in the structure and function of the normal and diseased nervous system. The Archives of Neurology & Psychiatry began publication in 1919 and, in 1959, became 2 separate journals: Archives of Neurology and Archives of General Psychiatry. In 2013, their names changed to JAMA Neurology and JAMA Psychiatry, respectively. JAMA Neurology is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.