Polydopamine-engineered FRET microspheres for robust dual-readout multiplexed nucleic acid analysis.

IF 4.2 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-08-15 DOI:10.1039/d5cc03811a

Xinrui He,Yilei Zhu,Yu Guo,Jing Chen,Liwen Tang,Jie Song,Yi Chen,Dongzhi Yang,Chao Guo

引用次数: 0

Abstract

We present a polydopamine-engineered FRET-encoded microsphere platform that ensures stable spectral encoding, efficient decoding, improved dispersion, and reproducible high-density DNA immobilization (∼0.1 nmol mg-1), enabling robust and sensitive multiplexed nucleic acid analysis with low background signals.

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多多巴胺工程FRET微球稳健双读出多路核酸分析。

我们提出了一种多多巴胺工程的fret编码微球平台，可确保稳定的光谱编码，高效解码，改善色散和可重复的高密度DNA固定（~ 0.1 nmol mg-1），实现低背景信号下鲁棒和敏感的多路核酸分析。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.