Genomic and immunogenomic profiling of extramedullary acute myeloid leukemia reveals actionable clonal branching and frequent immune editing

IF 11.6 1区医学 Q1 HEMATOLOGY

Blood Cancer Journal Pub Date : 2025-08-13 DOI:10.1038/s41408-025-01345-2

Clément Collignon, Tucker Hansen, Colin Hercus, Marianna B. Ruzinova, Gabrielle Roth Guepin, Caroline Bonmati, Marie Thérèse Rubio, Pierre Feugier, Mélanie Gaudfrin, Hervé Sartelet, Marion Divoux, Marc Muller, Sharon Heath, Geoffrey L. Uy, David H. Spencer, David Y. Chen, Simona Pagliuca, Francesca Ferraro

引用次数: 0

Abstract

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髓外急性髓系白血病的基因组和免疫基因组分析揭示了可操作的克隆分支和频繁的免疫编辑

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Blood Cancer Journal ONCOLOGY-

CiteScore

16.70

自引率

2.30%

发文量

153

审稿时长

>12 weeks

期刊介绍： Blood Cancer Journal is dedicated to publishing high-quality articles related to hematologic malignancies and related disorders. The journal welcomes submissions of original research, reviews, guidelines, and letters that are deemed to have a significant impact in the field. While the journal covers a wide range of topics, it particularly focuses on areas such as: Preclinical studies of new compounds, especially those that provide mechanistic insights Clinical trials and observations Reviews related to new drugs and current management of hematologic malignancies Novel observations related to new mutations, molecular pathways, and tumor genomics Blood Cancer Journal offers a forum for expedited publication of novel observations regarding new mutations or altered pathways.