{"title":"Comparative analysis of the pathogenesis in Crohn's disease and ulcerative colitis.","authors":"Himanshu Agrawal, Nikhil Gupta","doi":"10.3748/wjg.v31.i29.109892","DOIUrl":null,"url":null,"abstract":"<p><p>This article discusses Yang and Zhang's review on Crohn's disease and ulcerative colitis pathogenesis, emphasizing immune dysregulation, genetics, microbiota, and environmental factors. It highlights the need for personalized approaches, longitudinal studies, and better diagnostic tools to improve treatment strategies and patient outcomes in inflammatory bowel disease.</p>","PeriodicalId":23778,"journal":{"name":"World Journal of Gastroenterology","volume":"31 29","pages":"109892"},"PeriodicalIF":5.4000,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12336979/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"World Journal of Gastroenterology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3748/wjg.v31.i29.109892","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
This article discusses Yang and Zhang's review on Crohn's disease and ulcerative colitis pathogenesis, emphasizing immune dysregulation, genetics, microbiota, and environmental factors. It highlights the need for personalized approaches, longitudinal studies, and better diagnostic tools to improve treatment strategies and patient outcomes in inflammatory bowel disease.
期刊介绍:
The primary aims of the WJG are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in gastroenterology and hepatology.