Arteritic Anterior Ischemic Optic Neuropathy in Takayasu Arteritis: An Ominous Systemic Sign?

IF 1.5 Q3 OPHTHALMOLOGY

Journal of Ophthalmic & Vision Research Pub Date : 2025-07-30 eCollection Date: 2025-01-01 DOI:10.18502/jovr.v20.14442

Kaviyapriya Natarajan, Amit Kumar Deb, Hemanth Ramachandar, Disha Agarwal, Augustine Jose, Shreyas Temkar

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Abstract

Purpose: To report a case of a patient diagnosed with arteritic anterior ischemic optic neuropathy, who was later diagnosed with a severe form of Takayasu arteritis (TA).

Case report: A 34-year-old lady presented with a sudden, painful loss of vision in the left eye for four months associated with headache and jaw claudication. Ocular examination revealed features suggestive of arteritic anterior ischemic optic neuropathy and microaneurysms scattered throughout the fundus in both eyes, consistent with Takayasu retinopathy. General examination and investigations, including CT aortogram, confirmed the diagnosis of TA. Despite being put on maximal immunosuppression, she developed severe systemic manifestations within the next three months and passed away due to the illness.

Conclusion: AION as a presenting feature in the setting of TA is uncommon, and its occurrence may indicate a progressive course and poor systemic outcomes.

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高须动脉炎的动脉前缺血性视神经病变：一种不祥的全身征象？

目的：报告一例被诊断为动脉前缺血性视神经病变的患者，后来被诊断为严重的Takayasu动脉炎（TA）。病例报告：一名34岁女性因左眼突然疼痛性视力丧失四个月，并伴有头痛和下颚跛行。眼部检查显示提示动脉前缺血性视神经病变和双眼眼底散在性微动脉瘤，符合高松视网膜病变。一般检查和调查，包括CT主动脉摄影，证实了TA的诊断。尽管进行了最大限度的免疫抑制，但她在接下来的三个月内出现了严重的全身表现，并因疾病而去世。结论：AION作为TA的临床表现并不常见，它的出现可能预示着一个渐进的过程和较差的全身预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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