{"title":"Pancreatic Doppelgängers: A Case of Misdiagnosed Identity.","authors":"Aditya Kler, Nirjhar Dutta, Jake Theis, Daniela Guerrero Vinsard","doi":"10.14309/crj.0000000000001796","DOIUrl":null,"url":null,"abstract":"<p><p>IgG-4 related disease (IgG4-RD) is an autoimmune disease that can affect multiple organs and mimic adenocarcinoma of the pancreas. We describe the case of a 74-year-old man who presented with pancreatic mass and biliary obstruction. He was initially diagnosed with pancreatic adenocarcinoma and was started on chemotherapy. Eventually, he was diagnosed with IgG-4 related disease with autoimmune pancreatitis type 1 and IgG-4 sclerosing cholangitis with rapid improvement of symptoms and clinical findings after receiving steroid therapy.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 8","pages":"e01796"},"PeriodicalIF":0.5000,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12338298/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACG Case Reports Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14309/crj.0000000000001796","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
IgG-4 related disease (IgG4-RD) is an autoimmune disease that can affect multiple organs and mimic adenocarcinoma of the pancreas. We describe the case of a 74-year-old man who presented with pancreatic mass and biliary obstruction. He was initially diagnosed with pancreatic adenocarcinoma and was started on chemotherapy. Eventually, he was diagnosed with IgG-4 related disease with autoimmune pancreatitis type 1 and IgG-4 sclerosing cholangitis with rapid improvement of symptoms and clinical findings after receiving steroid therapy.
期刊介绍:
ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.