{"title":"mSphere of Influence: From pixels to parasite insight-cryo-EM is rewiring apicomplexan cell biology.","authors":"Li-Av Segev-Zarko","doi":"10.1128/msphere.00231-25","DOIUrl":null,"url":null,"abstract":"<p><p>Li-av Segev Zarko studies the nanomachines that apicomplexan parasites deploy to break into host cells. In this mSphere of Influence article, she reflects on how breakthrough cryo-electron microscopy studies published between 2018 and 2021 reshaped her view of what the ever-advancing field of structural biology can reveal about molecular and cellular parasitology.</p>","PeriodicalId":19052,"journal":{"name":"mSphere","volume":" ","pages":"e0023125"},"PeriodicalIF":3.1000,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12482150/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"mSphere","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1128/msphere.00231-25","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/11 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Li-av Segev Zarko studies the nanomachines that apicomplexan parasites deploy to break into host cells. In this mSphere of Influence article, she reflects on how breakthrough cryo-electron microscopy studies published between 2018 and 2021 reshaped her view of what the ever-advancing field of structural biology can reveal about molecular and cellular parasitology.
期刊介绍:
mSphere™ is a multi-disciplinary open-access journal that will focus on rapid publication of fundamental contributions to our understanding of microbiology. Its scope will reflect the immense range of fields within the microbial sciences, creating new opportunities for researchers to share findings that are transforming our understanding of human health and disease, ecosystems, neuroscience, agriculture, energy production, climate change, evolution, biogeochemical cycling, and food and drug production. Submissions will be encouraged of all high-quality work that makes fundamental contributions to our understanding of microbiology. mSphere™ will provide streamlined decisions, while carrying on ASM''s tradition for rigorous peer review.