Probabilistic Mapping of Magnetic Resonance-Guided Focused Ultrasound (MRgFUS) Thalamotomy Targets in Essential Tremor and Tremor-Dominant Parkinson's Disease: Insights from a German Cohort.

IF 7.6 1区医学 Q1 CLINICAL NEUROLOGY

Movement Disorders Pub Date : 2025-08-08 DOI:10.1002/mds.70003

Jonas Krauss,Neeraj Upadhyay,Veronika Purrer,Valeri Borger,Marcel Daamen,Hannah Weiland,Angelika Maurer,Carsten Schmeel,Alexander Radbruch,Markus Essler,Ullrich Wüllner,Henning Boecker

引用次数: 0

Abstract

Precise targeting in magnetic resonance-guided focused ultrasound (MRgFUS) is critical for effective tremor control in essential tremor and tremor-dominant Parkinson's disease, as small deviations can reduce efficacy or cause side effects. In our cohort, sweetspots were identified at Montreal Neurological Institute (MNI) coordinates x = -12.4, y = -17.5, z = -1.7 (ET) and x = -13.4, y = -19.8, z = -3.0 (TDPD).

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磁共振引导聚焦超声（MRgFUS）丘脑切开术在特发性震颤和震颤显性帕金森病中的目标的概率映射：来自德国队列的见解。

磁共振引导聚焦超声（MRgFUS）的精确定位对于原发性震颤和震颤显性帕金森病的有效震颤控制至关重要，因为微小的偏差可能会降低疗效或引起副作用。在我们的队列中，甜点在蒙特利尔神经学研究所（MNI）坐标x = -12.4, y = -17.5, z = -1.7 （ET）和x = -13.4, y = -19.8, z = -3.0 （TDPD）被确定。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Movement Disorders 医学-临床神经学

CiteScore

13.30

自引率

8.10%

发文量

371

审稿时长

12 months

期刊介绍： Movement Disorders publishes a variety of content types including Reviews, Viewpoints, Full Length Articles, Historical Reports, Brief Reports, and Letters. The journal considers original manuscripts on topics related to the diagnosis, therapeutics, pharmacology, biochemistry, physiology, etiology, genetics, and epidemiology of movement disorders. Appropriate topics include Parkinsonism, Chorea, Tremors, Dystonia, Myoclonus, Tics, Tardive Dyskinesia, Spasticity, and Ataxia.