Rules of partitioning

IF 66.8 1区医学 Q1 ONCOLOGY

Nature Reviews Cancer Pub Date : 2025-08-08 DOI:10.1038/s41568-025-00866-z

Anna Dart

引用次数: 0

Abstract

Lyons et al. explored the rules of specificity and function for condensates formed by oncogenic fusion proteins, and identified a common molecular signature in these oncoproteins that compartmentalizes RNA polymerase II to confer an increase in gene activation and consequent cancer phenotypes.

Abstract Image

查看原文本刊更多论文

划分规则

Lyons等人探索了由致癌融合蛋白形成的凝聚物的特异性和功能规则，并在这些癌蛋白中发现了一个共同的分子特征，该特征使RNA聚合酶II区隔，从而赋予基因激活和随后的癌症表型增加。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Nature Reviews Cancer 医学-肿瘤学

CiteScore

111.90

自引率

0.40%

发文量

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Cancer, a part of the Nature Reviews portfolio of journals, aims to be the premier source of reviews and commentaries for the scientific communities it serves. The correct abbreviation for abstracting and indexing purposes is Nat. Rev. Cancer. The international standard serial numbers (ISSN) for Nature Reviews Cancer are 1474-175X (print) and 1474-1768 (online). Unlike other journals, Nature Reviews Cancer does not have an external editorial board. Instead, all editorial decisions are made by a team of full-time professional editors who are PhD-level scientists. The journal publishes Research Highlights, Comments, Reviews, and Perspectives relevant to cancer researchers, ensuring that the articles reach the widest possible audience due to their broad scope.