The people behind the papers - Chen Pan and Keisuke Shimada.

IF 3.6 2区生物学 Q1 DEVELOPMENTAL BIOLOGY

Development Pub Date : 2025-08-01 Epub Date: 2025-08-07 DOI:10.1242/dev.205120

引用次数: 0

Abstract

Pyruvate dehydrogenase E1 subunit alpha 2 (PDHA2) is a testis-specific mitochondrial protein involved in energy metabolism and spermatogenesis. In their study, Keisuke Shimada and colleagues show that PDHA2 is crucial for normal spermatogenesis and it likely compensates for Pdha1, which is normally silenced during meiosis, in male germ cells. To find out more about their work, we spoke to the first author, Chen Pan, and the corresponding author, Keisuke Shimada, Associate Professor at the Laboratory of Disease Models, School of Veterinary Medicine, Rakuno Gakuen University, Japan.

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这些文件背后的人——陈潘和岛田圭介。

丙酮酸脱氢酶E1亚基α 2 （PDHA2）是睾丸特异性线粒体蛋白，参与能量代谢和精子发生。在他们的研究中，Keisuke Shimada和他的同事们表明，PDHA2对正常的精子发生至关重要，它可能会补偿在男性生殖细胞减数分裂期间通常沉默的Pdha1。为了进一步了解他们的工作，我们采访了第一作者Chen Pan和通讯作者Keisuke Shimada，他是日本乐野学园大学兽医学院疾病模型实验室的副教授。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Development 生物-发育生物学

CiteScore

6.70

自引率

4.30%

发文量

433

审稿时长

3 months

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