Carbon ion radiotherapy as a dose escalation tool in the treatment of primary high-risk prostate cancer.

IF 2.2 3区 医学 Q2 UROLOGY & NEPHROLOGY
Current Opinion in Urology Pub Date : 2025-09-01 Epub Date: 2025-07-17 DOI:10.1097/MOU.0000000000001327
Matthias Moll, Piero Fossati, Carola Lütgendorf-Caucig, Eugen Hug
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引用次数: 0

Abstract

Purpose of review: Prostate cancer is the most common cancer in men. In the high-risk group, carbon ion radiotherapy (CIRT) is being developed as a state-of-the-art alternative for treatment.

Recent findings: Data conducted from studies in Japan, as published by the J-CROS group, suggest that CIRT provides a tool to deliver a treatment for high-risk prostate cancer that delivers tumour control similar to a brachytherapy boost, but without the associated increase in toxicity.

Summary: While a considerable number of patients has been treated with CIRT, a randomized controlled trial showing the benefits of low toxicity while maintaining excellent tumour control has not yet been published and is highly warranted.

碳离子放疗作为一种剂量递增治疗原发性高危前列腺癌的工具。
综述目的:前列腺癌是男性最常见的癌症。在高危人群中,碳离子放射治疗(CIRT)正在发展成为一种最先进的治疗方法。最近的发现:J-CROS小组发表的日本研究数据表明,CIRT为高风险前列腺癌的治疗提供了一种工具,可以提供类似于近距离治疗的肿瘤控制,但没有相关的毒性增加。摘要:虽然相当多的患者已经接受了CIRT治疗,但一项随机对照试验显示,在保持良好的肿瘤控制的同时,低毒性的益处尚未发表,这是非常有根据的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Current Opinion in Urology
Current Opinion in Urology 医学-泌尿学与肾脏学
CiteScore
5.00
自引率
4.00%
发文量
140
审稿时长
6-12 weeks
期刊介绍: ​​​​​​​​Current Opinion in Urology delivers a broad-based perspective on the most recent and most exciting developments in urology from across the world. Published bimonthly and featuring ten key topics – including focuses on prostate cancer, bladder cancer and minimally invasive urology – the journal’s renowned team of guest editors ensure a balanced, expert assessment of the recently published literature in each respective field with insightful editorials and on-the-mark invited reviews.
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